Comment on Crews et al. Role and Determinants of Adherence to Off-loading in Diabetic Foot Ulcer Healing: A Prospective Investigation. Diabetes Care 2016;39:1371–1377

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Comment on Crews et al. Role and Determinants of Adherence to Off-loading in Diabetic Foot Ulcer Healing: A Prospective Investigation. Diabetes Care 2016;39:1371-1377.

We were pleased that van Netten et al. (1) appreciate the importance of our article (2) substantiating the relationship between adherence to off-loading modalities and healing of diabetic foot ulcers (DFUs). Their letter contained several comments regarding our article that we address here. The first comment by van Netten et al. is regarding the rationale for using a surrogate clinical outcome ...

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Role and Determinants of Adherence to Off-loading in Diabetic Foot Ulcer Healing: A Prospective Investigation

OBJECTIVE Studies indicate that off-loading adherence is low in patients with diabetic foot ulcers (DFUs), which may subsequently delay healing. However, there is little empirical evidence for this relationship or the factors that influence adherence. RESEARCH DESIGN AND METHODS This prospective, multicenter, international study of 79 (46 from the U.K. and 33 the U.S.) persons with type 2 dia...

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Comment on Ferrannini et al. Diabetes Care 2016;39:1108-1114. Comment on Mudaliar et al. Diabetes Care 2016;39:1115-1122.

In their recent articles, Ferrannini et al. (1) and Mudaliar et al. (2) suggest that increased ketonemia, improving heart function, might explain the positive results of the BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME) study. This suggestion perfectly fits with our recently published hypothesis that glucagon could be the key...

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Response to comment on: Löndahl et al. Hyperbaric Oxygen Therapy Facilitates Healing of Chronic Foot Ulcers in Patients With Diabetes. Diabetes Care 2010;33:998–1003

There is increasing evidence for the use of hyperbaric oxygen therapy (HBOT) in selected patients with chronic diabetic foot ulcers (1). However, several issues still need to be answered, including health economics. In an editorial commenting on our study, Lipsky and Berendt (2) reported costs between $50,000 and $200,000 for a full course of HBOT treatment in the U.S. Van der Staal et al. (3) ...

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Diabetic foot ulcer--a prospective study.

OBJECTIVE To detect "Feet at Risk" early, its early diagnosis and treatment of foot ulceration to prevent amputation. SETTING AND METHOD One hundred patients with diabetic foot problems were seen at Baqai Institute of Diabetology and Endocrinology from 06-01-97 to 14-04-99. Each Patient was examined for peripheral pulses, sensations and reflexes, for dryness of skin, deformity, callus and nai...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2016

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc16-1542